Proposed project will have a significant impact on the development of science at national but also international level since expected results will contribute greatly to the treatment protocols of the patients suffering from chronic wounds which will be directed towards personalized approaches that will lower the time needed for chronic wounds to heal and also enable more economic and approach that will be more comfortable for the patients. This research will greatly influence the health care of patients in our country but scientific data will contribute to the global scientific community and will enable the development of novel therapeutic personalized approaches in this medical field.